Fever, cardiac symptoms and signs, and migrating inflammation of the large joints, usually starting in the legs and migrating upward
Can occur 2–6 wk after streptococcal pharyngitis.
Rheumatic fever is a non-suppurative, acute inflammatory complication of group A streptococcal infection, causing combinations of arthritis, carditis, subcutaneous nodules, erythema marginatum, and chorea.
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