The premenstrual syndrome is a recurrent, variable cluster of troublesome physical and emotional symptoms that develop during the 7–14 days before the onset of menses and subside when menstruation occurs. The syndrome intermittently affects about 40% of all premenopausal women, primarily those 25–40 years of age. In about 10–15% of affected women, the syndrome may be severe. Although not every woman experiences all the symptoms or signs at one time, many describe bloating, breast pain, ankle swelling, a sense of increased weight, skin disorders, irritability, aggressiveness, depression, inability to concentrate, libido change, lethargy, and food cravings. The cause of premenstrual syndrome is still uncertain but attributed to female hormonal fluctuations. Psychosocial factors also may play a role.
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